Midterm clinical result of tissue-engineered vascular autografts seeded with autologous bone marrow cells.

@article{Shinoka2005MidtermCR,
  title={Midterm clinical result of tissue-engineered vascular autografts seeded with autologous bone marrow cells.},
  author={Toshiharu Shin'oka and Goki Matsumura and Narutoshi Hibino and Yuji Naito and Manabu Watanabe and Takeshi Konuma and Takahiko Sakamoto and Masayoshi Nagatsu and Hiromi Kurosawa},
  journal={The Journal of thoracic and cardiovascular surgery},
  year={2005},
  volume={129 6},
  pages={1330-8}
}
OBJECTIVE Prosthetic and bioprosthetic materials currently in use lack growth potential and therefore must be repeatedly replaced in pediatric patients as they grow. Tissue engineering is a new discipline that offers the potential for creating replacement structures from autologous cells and biodegradable polymer scaffolds. In May 2000, we initiated clinical application of tissue-engineered vascular grafts seeded with cultured cells. However, cell culturing is time-consuming, and xenoserum must… CONTINUE READING