Midodrine for orthostatic hypotension and recurrent reflex syncope

  title={Midodrine for orthostatic hypotension and recurrent reflex syncope},
  author={Ariel Izcovich and Carlos Gonz{\'a}lez Malla and Mat{\'i}as E Manzotti and Hugo Norberto Catalano and Gordon H. Guyatt},
  pages={1170 - 1177}
Objective: Symptomatic orthostatic hypotension (SOH) and recurrent reflex syncope (RRS) can be disabling. Midodrine has been proposed in the management of patients with these conditions but its impact on patient important outcomes remains uncertain. We performed a systematic review to evaluate the efficacy and safety of midodrine in patients with SOH and RRS. Methods: We searched multiple electronic databases without language restriction from their inception to June 2013. We included randomized… 

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