Midline radial glia translocation and corpus callosum formation require FGF signaling

@article{Smith2006MidlineRG,
  title={Midline radial glia translocation and corpus callosum formation require FGF signaling},
  author={Karen M{\"u}ller Smith and Yasushi Ohkubo and Maria Elisabetta Maragnoli and Mladen-Roko Rasin and Michael Louis Schwartz and Nenad Sestan and Flora M Vaccarino},
  journal={Nature Neuroscience},
  year={2006},
  volume={9},
  pages={787-797}
}
Midline astroglia in the cerebral cortex develop earlier than other astrocytes through mechanisms that are still unknown. We show that radial glia in dorsomedial cortex retract their apical endfeet at midneurogenesis and translocate to the overlaying pia, forming the indusium griseum. These cells require the fibroblast growth factor receptor 1 (Fgfr1) gene for their precocious somal translocation to the dorsal midline, as demonstrated by inactivating the Fgfr1 gene in radial glial cells and by… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 52 REFERENCES

Fgf8 regulates the development of intra-neocortical projections.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 2004

Fibroblast growth factor receptor signaling promotes radial glial identity and interacts with Notch1 signaling in telencephalic progenitors

K Yoon
  • J. Neurosci
  • 2004