Midlife predictors of Alzheimer's disease.

  title={Midlife predictors of Alzheimer's disease.},
  author={Barbara B. Bendlin and Cynthia M. Carlsson and Carey E. Gleason and Sterling C. Johnson and Aparna Sodhi and Catherine L. Gallagher and Luigi Puglielli and Corinne D. Engelman and Michele L. Ries and Genwen Xu and Whitney Wharton and Sheena Asthana},
  volume={65 2},
Factors contributing to increased risk for Alzheimer's disease (AD) include age, sex, genes, and family history of AD. Several risk factors for AD are endogenous; however, accumulating evidence implicates modifiable risk factors in the pathogenesis of AD. Although the continued task of identifying new genes will be critical to learning more about the disease, several research findings suggest that potentially alterable environmental factors influence genetic contributions, providing targets for… CONTINUE READING

From This Paper

Topics from this paper.


Publications citing this paper.
Showing 1-10 of 16 extracted citations

Prion protein and aging

Front. Cell Dev. Biol. • 2014
View 11 Excerpts
Highly Influenced

Influence of family history of dementia in the development and progression of late-onset Alzheimer's disease.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics • 2016


Publications referenced by this paper.
Showing 1-10 of 131 references

Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo.

Proceedings of the National Academy of Sciences of the United States of America • 2003
View 3 Excerpts
Highly Influenced

IC-P-043 functional perfusion MRI shows decreased hippocampal signal with normal aging in ApoE4 carriers. Alzheimers Demen 2006;2(3 (Suppl. 1)):S671–2

AS Fleisher, MW Bondi, C Taylor
View 2 Excerpts

White matter is altered with parental family history of Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association • 2010
View 2 Excerpts

Age, neuropathology, and dementia.

The New England journal of medicine • 2009
View 2 Excerpts

Alcohol consumption as a risk factor for dementia and cognitive decline: meta-analysis of prospective studies.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry • 2009

Similar Papers

Loading similar papers…