Midkine expression is associated with clinicopathological features and BRAF mutation in papillary thyroid cancer

@article{Shao2013MidkineEI,
  title={Midkine expression is associated with clinicopathological features and BRAF mutation in papillary thyroid cancer},
  author={Hua Shao and Xiaohui Yu and Cuifang Wang and Qiang Wang and Haixia Guan},
  journal={Endocrine},
  year={2013},
  volume={46},
  pages={285-291}
}
The objective of this study is to detect the expression of midkine (MK) in papillary thyroid cancer (PTC) and to evaluate whether MK expression is associated with clinicopathological features and BRAF mutation in PTC. The expression of MK in samples from 200 cases of PTC, 60 cases of adenomatoid nodule of thyroid, and 40 samples of tumor-adjacent normal thyroid tissue were assessed with immunohistochemistry. The BRAF mutation was detected by direct sequencing. The relationships between MK… CONTINUE READING

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