Midkine and pleiotrophin have bactericidal properties: preserved antibacterial activity in a family of heparin-binding growth factors during evolution.

Abstract

Antibacterial peptides of the innate immune system combat pathogenic microbes, but often have additional roles in promoting inflammation and as growth factors during tissue repair. Midkine (MK) and pleiotrophin (PTN) are the only two members of a family of heparin-binding growth factors. They show restricted expression during embryogenesis and are up… (More)
DOI: 10.1074/jbc.M109.081232

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@article{Svensson2010MidkineAP, title={Midkine and pleiotrophin have bactericidal properties: preserved antibacterial activity in a family of heparin-binding growth factors during evolution.}, author={Sara L Svensson and Mukesh Pasupuleti and Bj{\"o}rn Walse and Martin Malmsten and Matthias M{\"o}rgelin and Camilla Sj{\"o}gren and Anders I. Olin and Mattias Collin and Artur Schmidtchen and Ruth H Palmer and Arne Egesten}, journal={The Journal of biological chemistry}, year={2010}, volume={285 21}, pages={16105-15} }