Middle East respiratory syndrome coronavirus neutralising serum antibodies in dromedary camels: a comparative serological study

@article{Reusken2013MiddleER,
  title={Middle East respiratory syndrome coronavirus neutralising serum antibodies in dromedary camels: a comparative serological study},
  author={Chantal B.E.M. Reusken and Bart L. Haagmans and Marcel Alexander M{\"u}ller and Carlos Guti{\'e}rrez and G J Godeke and Benjamin Meyer and Doreen Muth and V. Stalin Raj and Laura Smits-de Vries and Victor Max Corman and Jan Felix Drexler and Saskia L. Smits and Yasmin el Tahir and Rita de Sousa and Janko van Beek and Norbert Nowotny and Kees van Maanen and Ezequiel Hidalgo‐Hermoso and Berend Jan Bosch and Peter J. M. Rottier and Albert D.M.E. Osterhaus and Christian Gort{\'a}zar-Schmidt and Christian Drosten and Marion P. G. Koopmans},
  journal={The Lancet. Infectious Diseases},
  year={2013},
  volume={13},
  pages={859 - 866}
}

Figures and Tables from this paper

Middle East respiratory syndrome coronavirus in dromedary camels: an outbreak investigation
Global status of Middle East respiratory syndrome coronavirus in dromedary camels: a systematic review
TLDR
All published data on MERS-coronavirus (CoV) in the global camel population is compiled and analysed to provide an overview of current knowledge on the distribution, spread and risk factors of infections in dromedary camels.
Middle East Respiratory Syndrome Coronavirus Infection in Dromedary Camels in Saudi Arabia
TLDR
Evidence is provided from a geographic and temporal survey of camels in the Kingdom of Saudi Arabia that MERS coronaviruses have been circulating in camels since at least 1992, are distributed countrywide, and can be phylogenetically classified into clades that correlate with outbreaks of the disease among humans.
Middle East Respiratory Syndrome Coronavirus Antibodies in Bactrian and Hybrid Camels from Dubai
TLDR
It is concluded that in addition to dromedaries, Bactrian and hybrid camels are also potential sources of MERS-CoV infection.
Middle East Respiratory Syndrome Coronavirus: Another Zoonotic Betacoronavirus Causing SARS-Like Disease
TLDR
Developing an effective camel MERS-CoV vaccine and implementing appropriate infection control measures may control the continuing epidemic.
Cross-sectional study of MERS-CoV-specific RNA and antibodies in animals that have had contact with MERS patients in Saudi Arabia
Sero‐prevalence of Middle East respiratory syndrome coronavirus (MERS‐CoV) specific antibodies in dromedary camels in Tabuk, Saudi Arabia
TLDR
Results may provide evidence that MERS‐CoV has previously infected dromedary camels in Tabuk and may support the possible role of Camels in the human infection.
Serosurvey for Middle East respiratory syndrome coronavirus antibody in dromedary camels and human patients at a secondary care hospital, Illela, Northwest Nigeria
TLDR
There is need for trained personnel, surveillance and diagnostic tools at border posts and animal markets due to the high seroprevalence obtained in this study for both camels and humans.
Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in Oman: Current Situation and Going Forward
TLDR
Seroprevalence studies revealed MERS-CoV exposure among all sampled domestic camels across Oman and two major healthcare-associated outbreaks due to superspreading events led to massive numbers of cases and excessive morbidity and mortality in several countries.
Middle East Respiratory Syndrome Coronavirus Antibody Reactors Among Camels in Dubai, United Arab Emirates, in 2005
TLDR
The results support the recent findings that infection with MERS‐CoV or a closely related virus is not a new occurrence in camels in the Middle East and a widespread pandemic may be less likely unless significant evolution of the virus allow accelerated infection and spread potential in the human population.
...
...

References

SHOWING 1-10 OF 41 REFERENCES
Close Relative of Human Middle East Respiratory Syndrome Coronavirus in Bat, South Africa
TLDR
The identification of a South Africa bat derived CoV that has an even closer phylogenetic relationship with MERS-CoV is reported, and is as close as that of SARS- coV and the most closely related bat coronavirus known.
Family cluster of Middle East respiratory syndrome coronavirus infections.
TLDR
A family case cluster of Mers-CoV infection is described, including the clinical presentation, treatment outcomes, and household relationships of three young men who became ill with MERS- coV infection after the hospitalization of an elderly male relative, who died of the disease.
Clinical features and virological analysis of a case of Middle East respiratory syndrome coronavirus infection
Hospital outbreak of Middle East respiratory syndrome coronavirus.
TLDR
Person-to-person transmission of MERS-CoV can occur in health care settings and may be associated with considerable morbidity and surveillance and infection-control measures are critical to a global public health response.
Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats.
  • S. Lau, P. Woo, K. Yuen
  • Biology
    Proceedings of the National Academy of Sciences of the United States of America
  • 2005
TLDR
In a surveillance study for CoV in noncaged animals from the wild areas of the Hong Kong Special Administration Region, a CoV closely related to SARS-CoV is identified from 23 (39%) of 59 anal swabs of wild Chinese horseshoe bats by using RT-PCR and the presence of a 29-bp insertion in ORF 8 of bat-SARS- coV genome suggests that it has a common ancestor with civet SARS -CoV.
Ecoepidemiology and Complete Genome Comparison of Different Strains of Severe Acute Respiratory Syndrome-Related Rhinolophus Bat Coronavirus in China Reveal Bats as a Reservoir for Acute, Self-Limiting Infection That Allows Recombination Events
TLDR
The present data suggest that SARSr-Rh-BatCoV causes acute, self-limiting infection in horseshoe bats, which serve as a reservoir for recombination between strains from different geographical locations within reachable foraging range.
Transmission scenarios for Middle East Respiratory Syndrome Coronavirus (MERS-CoV) and how to tell them apart.
TLDR
Whether the virus is capable of causing widespread human epidemics, and whether self-sustaining transmission is already under way, is assessed and how existing data, future investigations and analyses may help in reducing uncertainty and refining the public health risk assessment is discussed.
b Middle East respiratory syndrome coronavirus (MERS-CoV): update
TLDR
The number of reported cases increased markedly in April 2014 with 217 cases and 38 deaths; with such an increase in cases, it is much more likely that the US will see travelers who have been exposed and infected with MERS Co-V.
Antigenic and biological relationships between human coronavirus OC43 and neonatal calf diarrhoea coronavirus.
TLDR
Although OC43 and NCDCV share antigenic determinants, they possessed several different biological properties, including plaque morphology by the infectious centre assay, agglutination of 1-day-old chick erythrocytes and resistance of haemagglutinin to physical and chemical treatments.
...
...