Microwave assisted synthesis and antimicrobial evaluation of symmetrical 1,2-Phenylenediamine Schiff’s base derivatives

  title={Microwave assisted synthesis and antimicrobial evaluation of symmetrical 1,2-Phenylenediamine Schiff’s base derivatives},
  author={Abdul M. Gbaj},
  journal={Pharmacy \& Pharmacology International Journal},
  • A. Gbaj
  • Published 6 September 2018
  • Chemistry, Biology
  • Pharmacy & Pharmacology International Journal
Schiff’s bases (imine) are compounds that are containing azomethine group [-HC=N-] in their structure, formed by condensation of an dynamic carbonyl compound with a primary amine.1,2 Schiff bases have also been shown to show a big range of biological activities, including anti-inflammatory, antibacterial, antifungal, antiproliferative, antimalarial, antiviral, and antipyretic pharmacological activities.3‒7 Azomethine or imine groups can be found in a variety of natural e.g. ancistrocladidine… 

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