Microvessel density and regulators of angiogenesis in malignant and nonmalignant prostate tissue

@article{Kaygusuz2006MicrovesselDA,
  title={Microvessel density and regulators of angiogenesis in malignant and nonmalignant prostate tissue},
  author={Gulsah Kaygusuz and Ozden Tulunay and S{\"u}mer Baltacı and Orhan Gogus},
  journal={International Urology and Nephrology},
  year={2006},
  volume={39},
  pages={841-850}
}
The aim of this study was to investigate the relationship between microvessel density (MVD), positive and negative angiogenic factors, and established prognostic factors in prostate cancer (PC), and, to clarify the effect of angiogenic factors to angiogenesis. The vascularization of neoplastic, non-neoplastic prostate tissue was determined by CD34 immunostaining. Angiogenetic mediators VEGF, bFGF, TSP-1, and p53 were studied by immunohistochemistry. Neovascularization and p53, VEGF, and TSP-1… Expand
Reconsideration of the clinical and histopathological significance of angiogenesis in prostate cancer: Usefulness and limitations of microvessel density measurement
  • Y. Miyata, H. Sakai
  • Medicine
  • International journal of urology : official journal of the Japanese Urological Association
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TLDR
The present review focuses on the variation in methodologies of measuring microvessel density in cancer tissues, including the selected area and the method used for (semi)quantification, and discusses the relationship between malignancy potential, tumor progression, and survival and differences in the antibodies used for detection of endothelial cells in detail. Expand
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  • International journal of urology : official journal of the Japanese Urological Association
  • 2016
TLDR
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Microvessel density is not increased in prostate cancer: digital imaging of routine sections and tissue microarrays.
TLDR
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Thrombospondin-1 in Urological Cancer: Pathological Role, Clinical Significance, and Therapeutic Prospects
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