Microvesicles released from human renal cancer stem cells stimulate angiogenesis and formation of lung premetastatic niche.

@article{Grange2011MicrovesiclesRF,
  title={Microvesicles released from human renal cancer stem cells stimulate angiogenesis and formation of lung premetastatic niche.},
  author={Cristina Grange and Marta Tapparo and Federica Collino and Loriana Vitillo and Christian Damasco and Maria Chiara Deregibus and Ciro Tetta and Benedetta Bussolati and Giovanni Camussi},
  journal={Cancer research},
  year={2011},
  volume={71 15},
  pages={5346-56}
}
Recent studies suggest that tumor-derived microvesicles (MV) act as a vehicle for exchange of genetic information between tumor and stromal cells, engendering a favorable microenvironment for cancer development. Within the tumor mass, all cell types may contribute to MV shedding, but specific contributions to tumor progression have yet to be established. Here we report that a subset of tumor-initiating cells expressing the mesenchymal stem cell marker CD105 in human renal cell carcinoma… CONTINUE READING
Highly Influential
This paper has highly influenced 14 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 295 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 51 references

Identification of a tumor-initiating stem cell population in human renal carcinomas

  • B Bussolati, S Bruno, GrangeC, U Ferrando, G. Camussi
  • FASEB J 2008;22:3696–705
  • 2008
Highly Influential
3 Excerpts

Similar Papers

Loading similar papers…