Microvesicles as novel biomarkers and therapeutic targets in transplantation medicine.

@article{Fleissner2012MicrovesiclesAN,
  title={Microvesicles as novel biomarkers and therapeutic targets in transplantation medicine.},
  author={Felix Fleissner and Yvonne G{\"o}rzig and Axel Haverich and Thomas Thum},
  journal={American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons},
  year={2012},
  volume={12 2},
  pages={289-97}
}
Microvesicles (MVs) including exosomes are emerging new biomarkers and potential regulators of inflammation and immunological processes. Such particles contain proteins and genetic information including DNA and microRNAs that may be of importance for cell/cell communication. However, their role during and after organ transplantation and immunomodulatory effects is only in its beginning of understanding. We here, in brief, introduce generation and biological importance of MVs, describe their… CONTINUE READING

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