Microvesicle-mediated transfer of genetic phenotype from lung to marrow cells.

Abstract

e21092 Background: We have previously shown that lung-derived microvesicles (MVs) can enter target marrow cells, resulting in increased levels of lung-specific mRNAs. Marrow which has been exposed to MVs also show increased production of pulmonary epithelial cells after transplantation into irradiated mice. The present studies have addressed the… (More)

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