Microvesicle Subsets in Sepsis Due to Community Acquired Pneumonia Compared to Faecal Peritonitis.

@article{Lashin2018MicrovesicleSI,
  title={Microvesicle Subsets in Sepsis Due to Community Acquired Pneumonia Compared to Faecal Peritonitis.},
  author={Hazem M S Lashin and Suchita Nadkarni and Silvia Oggero and Hefin R. Jones and Julian C. Knight and Charles J Hinds and Mauro Perretti},
  journal={Shock},
  year={2018},
  volume={49 4},
  pages={393-401}
}
RATIONALE Microvesicles (MV) act as a nonsoluble means of intercellular communication, with effector roles in disease pathogenesis and potentially as biomarkers. Previously, we reported that neutrophil MV expressing alpha-2-macroglobulin (A2MG) are protective in experimental sepsis and associate with survival in a small cohort of patients with sepsis due to community acquired pneumonia (CAP). OBJECTIVES To characterize MV profiles in sepsis due to CAP or fecal peritonitis (FP) and determine… CONTINUE READING