Microvascular recruitment is an early insulin effect that regulates skeletal muscle glucose uptake in vivo.

@article{Vincent2004MicrovascularRI,
  title={Microvascular recruitment is an early insulin effect that regulates skeletal muscle glucose uptake in vivo.},
  author={Michelle A. Vincent and Lucy H. Clerk and Jonathan R. Lindner and Alexander L. Klibanov and Michael S. G. Clark and Stephen Rattigan and Eugene J. Barrett},
  journal={Diabetes},
  year={2004},
  volume={53 6},
  pages={1418-23}
}
Insulin increases glucose disposal into muscle. In addition, in vivo insulin elicits distinct nitric oxide synthase-dependent vascular responses to increase total skeletal muscle blood flow and to recruit muscle capillaries (by relaxing resistance and terminal arterioles, respectively). In the current study, we compared the temporal sequence of vascular and metabolic responses to a 30-min physiological infusion of insulin (3 mU. min(-1). kg(-1), euglycemic clamp) or saline in rat skeletal… CONTINUE READING
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Insulin resistance, INSULIN’S DIRECT ENDOTHELIAL ACTION IN MUSCLE

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Capillary recruitment in muscle is a highly sensitive event in insulin action in vivo (Abstract)

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Skeletal muscle microvascular recruitment is more insulin sensitive than femoral blood flow or glucose disposal (Abstract)

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  • Diabetes 52 (Suppl
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Modest exercise enhances human skeletal muscle perfusion by capillary recruitment in the absence of changes in total blood flow (Abstract)

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