Microvascular perfusion upon exchange transfusion with stored red blood cells in normovolemic anemic conditions.

@article{Tsai2004MicrovascularPU,
  title={Microvascular perfusion upon exchange transfusion with stored red blood cells in normovolemic anemic conditions.},
  author={Amy G. Tsai and Pedro J. Cabrales and Marcos Intaglietta},
  journal={Transfusion},
  year={2004},
  volume={44 11},
  pages={1626-34}
}
BACKGROUND Transfusions are intended to augment oxygen-carrying capacity. The ability of fresh and stored red blood cells (RBCs) to maintain microvascular perfusion and oxygen delivery to the tissue has not been directly measured. STUDY DESIGN AND METHODS Microvascular responses to exchange transfusion with fresh and stored RBCs after acute isovolemic hemodilution with a plasma expander were investigated with the hamster window chamber model. In-vivo functional capillary density (FCD), blood… CONTINUE READING
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