Microvascular imaging: techniques and opportunities for clinical physiological measurements.

  title={Microvascular imaging: techniques and opportunities for clinical physiological measurements.},
  author={John Allen and Kevin Howell},
  journal={Physiological measurement},
  volume={35 7},
The microvasculature presents a particular challenge in physiological measurement because the vessel structure is spatially inhomogeneous and perfusion can exhibit high variability over time. This review describes, with a clinical focus, the wide variety of methods now available for imaging of the microvasculature and their key applications. Laser Doppler perfusion imaging and laser speckle contrast imaging are established, commercially-available techniques for determining microvascular… CONTINUE READING
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