Microvascular endowment in the developing chicken embryo lung.

  title={Microvascular endowment in the developing chicken embryo lung.},
  author={Andrew Ndegwa Makanya and Ruslan Hlushchuk and Oliver Baum and Nikolay Velinov and Matthias Ochs and Valentin Djonov},
  journal={American journal of physiology. Lung cellular and molecular physiology},
  volume={292 5},
In the current study, the contribution of the major angiogenic mechanisms, sprouting and intussusception, to vascular development in the avian lung has been demonstrated. Sprouting guides the emerging vessels to form the primordial vascular plexus, which successively surrounds and encloses the parabronchi. Intussusceptive angiogenesis has an upsurge from embryonic day 15 (E15) and contributes to the remarkably rapid expansion of the capillary plexus. Increased blood flow stimulates formation of… CONTINUE READING