Microvascular architecture and exchange in synovial joints.

  title={Microvascular architecture and exchange in synovial joints.},
  author={J. Rodney Levick},
  volume={2 3},
The microcirculation of the synovial lining of joints displays many fascinating adaptations to function. One primary function is to supply nutrients to the avascular cartilage, whose chondrocytes are metabolically active but are relatively vast distances from the nearest capillary (> 1 cm in the center of a human knee). Exchange is facilitated by a high density of fenestrated capillaries situated very close to the synovial surface (an arrangement disrupted in rheumatoid synovium) with… CONTINUE READING