Microvascular and mitochondrial dysfunction in the female F1 generation after gestational TiO2 nanoparticle exposure.

@article{Stapleton2015MicrovascularAM,
  title={Microvascular and mitochondrial dysfunction in the female F1 generation after gestational TiO2 nanoparticle exposure.},
  author={Phoebe A. Stapleton and Cody E. Nichols and Jinghai Yi and Carroll R. McBride and Valerie C. Minarchick and Danielle L. Shepherd and John Hollander and Timothy R. Nurkiewicz},
  journal={Nanotoxicology},
  year={2015},
  volume={9 8},
  pages={941-51}
}
Due to the ongoing evolution of nanotechnology, there is a growing need to assess the toxicological outcomes in under-studied populations in order to properly consider the potential of engineered nanomaterials (ENM) and fully enhance their safety. Recently, we and others have explored the vascular consequences associated with gestational nanomaterial exposure, reporting microvascular dysfunction within the uterine circulation of pregnant dams and the tail artery of fetal pups. It has been… CONTINUE READING
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