Microvascular anastomosis using a photochemical tissue bonding technique

@article{ONeill2007MicrovascularAU,
  title={Microvascular anastomosis using a photochemical tissue bonding technique},
  author={Anne C O'Neill and Jonathan M. Winograd and Jos{\'e} Luis Zeballos and Timothy S. Johnson and Mark A. Randolph and Kenneth E Bujold and Irene E Kochevar and Robert W. Redmond},
  journal={Lasers in Surgery and Medicine},
  year={2007},
  volume={39}
}
Photochemical tissue bonding (PTB) combines photoactive dyes with visible light to create fluid‐tight seals between tissue surfaces without causing collateral thermal damage. The potential of PTB to improve outcomes over standard of care microsurgical reanastomoses of blood vessels in ex vivo and in vivo models was evaluated. 
View on Wiley
ncbi.nlm.nih.gov
73 Citations
Highly Influential Citations
4
Background Citations
18
Methods Citations
6
Results Citations
2

73 Citations

Citation Type

Citation Type

Light‐activated tissue bonding for excisional wound closure: a split‐lesion clinical trial
TLDR
A novel tissue‐sealing technology, photoactivated tissue bonding (PTB), which immediately crosslinks proteins between tissue planes, thereby sealing on a molecular scale is developed.
Light‐activated sealing of skin wounds
TLDR
The goals of this study were to evaluate parameters influencing PTB in order to optimize its clinical efficacy and to determine whether PTB can be used to seal wounds in moderately to highly pigmented skin.
Light‐activated photosealing with human amniotic membrane strengthens bowel anastomosis in a hypotensive, trauma‐relevant swine model
TLDR
It is evaluated if crosslinked human amniotic membrane (xHAM) photosealed over the enteroenterostomy would augment anastomotic strength in a trauma‐relevant swine hemorrhagic shock model.
Chitosan-ECM bandages for photochemical tissue repair
  • A. Lauto, D. Mawad
  • Medicine, Biology
    2011 International Quantum Electronics Conference (IQEC) and Conference on Lasers and Electro-Optics (CLEO) Pacific Rim incorporating the Australasian Conference on Optics, Lasers and Spectroscopy and the Australian Conference on Optical Fibre Technology
  • 2011
TLDR
A new photochemically-activated adhesive bandage is developed to fix ECM on tissue without sutures to enhance wound healing in several reconstructive surgical procedures.
Phototoxicity is not associated with photochemical tissue bonding of skin
TLDR
These studies were designed to determine whether RB causes phototoxicity during closure of skin incisions with PTB to initiate photochemical crosslinking of wound surface proteins.
Comparison of Photochemical Crosslinking Versus Sutures for Bonding Conjunctival Grafts
To explore whether Rose Bengal‐induced photochemical crosslinking (RB‐PCL) can be a replacement for sutures in conjunctival autograft bonding, we compared the safety, operating time, postoperative…
A light‐activated amnion wrap strengthens colonic anastomosis and reduces peri‐anastomotic adhesions
TLDR
This work evaluated if a human amniotic membrane, sealed over the anastomotic line by PTB, increases the anASTomotic strength.
Photochemical repair of vocal fold microflap defects
To bond vocal fold flaps using a sutureless, nonthermal laser‐assisted method combining visible light and photosensitizing dyes to produce collagen crosslinks.
An intraluminal stent facilitates light-activated vascular anastomosis
TLDR
This study demonstrated successful use of an intraluminal stent for acute microvascular anastomosis using the PTB technique, however, the longer-term presence of the stent at theAnastomotic site led to thrombosis in multiple cases.
In vitro cell compatibility study of rose bengal–chitosan adhesives
TLDR
It was recently demonstrated that laser‐irradiated chitosan films, incorporating RB, bonded firmly to calf intestine in vitro, and it is required to investigate the possible cytotoxic effects of the RB–chitOSan adhesive on cells before testing its application to in vivo models.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 38 REFERENCES
Evaluation of photochemical tissue bonding for closure of skin incisions and excisions
TLDR
The objective was to compare PTB with standard sutures and the tissue adhesive, octyl cyanoacrylate, for closure of skin incisions and excisions.
Laser‐assisted microvascular anastomosis using CO2 and KTP/532 lasers
TLDR
The purpose of this investigation was to determine the feasibility of using the potassium titanyl phosphate (KTP) laser to perform LAMA and to compare it to CO2 LAMA in both arteries and veins.
Comparison of laser vascular welding, interrupted sutures, and continuous sutures in growing vascular anastomoses
TLDR
The argon laser‐assisted vascular anastomosis may solve the problems of conventional sutured anASTomosis, such as vascular stenosis and arrest of growth owing to a foreign‐body reaction to suture material.
Repair of small blood vessels with the neodymium-YAG laser: a preliminary report.
TLDR
A technique for repair of incisions in small blood vessels in the rat is described using a Neodymium-YAG laser and is considered to be relatively safe, and the potential use of the application in human surgery is indicated.
Contact diode laser microvascular anastomosis
TLDR
The authors have found that contact diode laser anastomosis can be performed in vessels as small as 1 mm in size using a 200‐μm flat tip synthetic sapphire probe.
Biodegradable polymer film reinforcement of an indocyanine green‐doped liquid albumin solder for laser‐assisted incision closure
The purpose of this study was to determine whether solid material reinforcement of a liquid albumin solder coagulum could improve the cohesive strength of the solder and, thus, the ultimate breaking…
Laser-assisted microsurgical anastomoses in traumatized blood vessels.
TLDR
Findings indicate that the laser technique may be a better option when working with traumatized vessels because of the critical nature of early patency rates, and improved results may be due to a reduction of suture material at the anastomotic site when using the lasers.
Non‐suture methods of vascular anastomosis
The main aim of performing a vascular anastomosis is to achieve maximal patency rates. An important factor to achieve that goal is to minimize damage to the vessel walls. Sutures inevitably induce…
Laser assisted microvascular anastomosis of arteries and veins: laser tissue welding.
Improved vascular tissue fusion using new light-activated surgical adhesive on a canine model.
TLDR
Initial results indicated that laser-assisted vascular repair using the new adhesives is safe, easy to perform, and contrary to conventional suturing, provides an immediate leak-free closure, thus greatly improving the clinical applicability of laser- assisted tissue repair.
...
1
2
3
4
...