Microvascular Endothelial Dysfunction in Sedentary, Obese Humans Is Mediated by NADPH Oxidase: Influence of Exercise Training.

@article{Favor2016MicrovascularED,
  title={Microvascular Endothelial Dysfunction in Sedentary, Obese Humans Is Mediated by NADPH Oxidase: Influence of Exercise Training.},
  author={Justin D La Favor and Gabriel S. Dubis and Huimin Yan and J. D. White and Margaret A. M. Nelson and Ethan J. Anderson and Robert C. Hickner},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={2016},
  volume={36 12},
  pages={
          2412-2420
        }
}
OBJECTIVE The objectives of this study were to determine the impact of in vivo reactive oxygen species (ROS) on microvascular endothelial function in obese human subjects and the efficacy of an aerobic exercise intervention on alleviating obesity-associated dysfunctionality. APPROACH AND RESULTS Young, sedentary men and women were divided into lean (body mass index 18-25; n=14), intermediate (body mass index 28-32.5; n=13), and obese (body mass index 33-40; n=15) groups. A novel microdialysis… CONTINUE READING
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