Microvascular Dysfunction and Cognitive Impairment

  title={Microvascular Dysfunction and Cognitive Impairment},
  author={T. Michael De Silva and Frank M. Faraci},
  journal={Cellular and Molecular Neurobiology},
The impact of vascular risk factors on cognitive function has garnered much interest in recent years. The appropriate distribution of oxygen, glucose, and other nutrients by the cerebral vasculature is critical for proper cognitive performance. The cerebral microvasculature is a key site of vascular resistance and a preferential target for small vessel disease. While deleterious effects of vascular risk factors on microvascular function are known, the contribution of this dysfunction to… CONTINUE READING


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