Microtubules tethered at epithelial cell junctions by dynein facilitate efficient junction assembly.

@article{Ligon2007MicrotubulesTA,
  title={Microtubules tethered at epithelial cell junctions by dynein facilitate efficient junction assembly.},
  author={Lee A. Ligon and Erika L. F. Holzbaur},
  journal={Traffic},
  year={2007},
  volume={8 7},
  pages={808-19}
}
Efficient remodeling of cell-cell adhesions is critical during development and morphogenesis. Junctional components must be specifically and rapidly transported to sites of junction assembly. In this study, we show a mechanism by which this targeted trafficking may occur. Microtubules target epithelial adherens junctions, and the number of microtubules both projecting to and tethered at sites of contact is increased during junction assembly, consistent with an increased need for new material at… CONTINUE READING
34 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 34 extracted citations

Similar Papers

Loading similar papers…