Microtubules in cell migration.

  title={Microtubules in cell migration.},
  author={Sandrine Etienne-Manneville},
  journal={Annual review of cell and developmental biology},
Migration is a polarized cellular process that opposes a protrusive front edge to a retracting trailing edge. From the front to the rear, actin-mediated forces sequentially promote cell protrusion, adhesion, contraction, and retraction. Over the past decade, microtubules have revealed their pivotal role in cell migration. Through their roles in cell mechanics, intracellular trafficking, and signaling, microtubules participate in all essential events leading to cell migration. The front-rear… CONTINUE READING

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CLASP 1 and CLASP 2 bind to EB 1 and regulate microtubule plus - end dynamics at the cell cortex

  • Y Mimori-Kiyosue, I Grigoriev, G Lansbergen, H Sasaki, C Matsui
  • J . Cell Biol .
  • 2005
Highly Influential
3 Excerpts

Distinct roles of talin and kindlin in regulating α 5 β 1 function and trafficking

  • C Margadant, M Kreft, de Groot D-J, JC Norman, A Sonnenberg
  • Curr . Biol .
  • 2012
1 Excerpt

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