Microtubule polarity and axis formation in the Drosophila oocyte.

  title={Microtubule polarity and axis formation in the Drosophila oocyte.},
  author={Josefa Steinhauer and Daniel Kalderon},
  journal={Developmental dynamics : an official publication of the American Association of Anatomists},
  volume={235 6},
The body axes of the fruit fly are established in mid-oogenesis by the localization of three mRNA determinants, bicoid, oskar, and gurken, within the oocyte. General mechanisms of RNA localization and cell polarization, applicable to many cell types, have emerged from investigation of these determinants in Drosophila oogenesis. Localization of these RNAs is dependent on the germline microtubules, which reorganize to form a polarized array at mid-oogenesis in response to a signaling relay… CONTINUE READING

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