Microtubule plus end-tracking proteins play critical roles in directional growth of hyphae by regulating the dynamics of cytoplasmic microtubules in Aspergillus nidulans.

@article{Zeng2014MicrotubulePE,
  title={Microtubule plus end-tracking proteins play critical roles in directional growth of hyphae by regulating the dynamics of cytoplasmic microtubules in Aspergillus nidulans.},
  author={Cui Jing Tracy Zeng and Hye-Ryun Kim and Irasema Vargas Arispuro and Jung-mi Kim and An-Chi Huang and Bo Ya Liu},
  journal={Molecular microbiology},
  year={2014},
  volume={94 3},
  pages={506-21}
}
Cytoplasmic microtubules (MTs) serve as a rate-limiting factor for hyphal tip growth in the filamentous fungus Aspergillus nidulans. We hypothesized that this function depended on the MT plus end-tracking proteins (+TIPs) including the EB1 family protein EBA that decorated the MT plus ends undergoing polymerization. The ebAΔ mutation reduced colony growth and the mutant hyphae appeared in an undulating pattern instead of exhibiting unidirectional growth in the control. These phenotypes were… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 69 references

Microtubule +TIPs at a glance.

Journal of cell science • 2010
View 5 Excerpts
Highly Influenced

The role of microtubules in rapid hyphal tip growth of Aspergillus nidulans.

Molecular biology of the cell • 2005
View 11 Excerpts
Highly Influenced

Cytoplasmic dynein is involved in nuclear migration in Aspergillus nidulans.

Proceedings of the National Academy of Sciences of the United States of America • 1994
View 4 Excerpts
Highly Influenced

Microtubule tip-interacting proteins: a view from both ends.

Current opinion in cell biology • 2011
View 4 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…