Microtubule disassembly delays the G2–M transition in vertebrates

Abstract

When cell cultures in growth are treated with drugs that cause microtubules to disassemble, the mitotic index (MI) progressively increases as the cells accumulate in a C-mitosis. For many cell types, however, including rat kangaroo kidney PtK(1) cells, the MI does not increase during the first several hours of treatment [1-3] (Figure 1). This 'lag' implies… (More)
DOI: 10.1016/S0960-9822(00)00678-3

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@article{Rieder2000MicrotubuleDD, title={Microtubule disassembly delays the G2–M transition in vertebrates}, author={Conly L. Rieder and R. Cole}, journal={Current Biology}, year={2000}, volume={10}, pages={1067-1070} }