Microtubule biogenesis and cell shape in Ochromonas. II. The role of nucleating sites in shape development.

@article{Brown1973MicrotubuleBA,
  title={Microtubule biogenesis and cell shape in Ochromonas. II. The role of nucleating sites in shape development.},
  author={Darren L. Brown and G. Benjamin Bouck},
  journal={The Journal of cell biology},
  year={1973},
  volume={56 2},
  pages={360-78}
}
The proposal made in the preceding paper that the species-specific shape of Ochromonas is mediated by cytoplasmic microtubules which are related to two nucleating sites has been experimentally verified. Exposure of cells to colchicine or hydrostatic pressure causes microtubule disassembly and a correlative loss of cell shape in a posterior to anterior direction. Upon removal of colchicine or release of pressure, cell shape regenerates and microtubules reappear, first in association with the… CONTINUE READING

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