Microtubule-associated protein 2 (MAP2) associates with the NMDA receptor and is spatially redistributed within rat hippocampal neurons after oxygen-glucose deprivation.

@article{Buddle2003MicrotubuleassociatedP2,
  title={Microtubule-associated protein 2 (MAP2) associates with the NMDA receptor and is spatially redistributed within rat hippocampal neurons after oxygen-glucose deprivation.},
  author={Michele M. Buddle and Eric S Eberhardt and Lauren H Ciminello and Tal Levin and Richard E Wing and Kathleen DiPasquale and Kathleen M. Raley-Susman},
  journal={Brain research},
  year={2003},
  volume={978 1-2},
  pages={38-50}
}
MAP2 (microtubule-associated protein 2) is a cytoskeletal phosphoprotein that regulates the dynamic assembly characteristics of microtubules and appears to provide scaffolding for organelle distribution into the dendrites and for the localization of signal transduction apparatus in dendrites, particularly near spines. MAP2 is degraded after ischemia and other metabolic insults, but the time course and initial triggers of that breakdown are not fully understood. This study determined that MAP2… CONTINUE READING