Microtubule assembly during mitosis - from distinct origins to distinct functions?

@article{Meunier2012MicrotubuleAD,
  title={Microtubule assembly during mitosis - from distinct origins to distinct functions?},
  author={Sylvain Meunier and Isabelle Vernos},
  journal={Journal of cell science},
  year={2012},
  volume={125 Pt 12},
  pages={2805-14}
}
The mitotic spindle is structurally and functionally defined by its main component, the microtubules (MTs). The MTs making up the spindle have various functions, organization and dynamics: astral MTs emanate from the centrosome and reach the cell cortex, and thus have a major role in spindle positioning; interpolar MTs are the main constituent of the spindle and are key for the establishment of spindle bipolarity, chromosome congression and central spindle assembly; and kinetochore-fibers are… CONTINUE READING
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