Microtubule actin cross‐linking factor 1, a novel potential target in cancer

  title={Microtubule actin cross‐linking factor 1, a novel potential target in cancer},
  author={Zhiping Miao and Arshad Ali and Lifang Hu and Fan Zhao and Chong Yin and Chu Chen and Tuanmin Yang and Airong Qian},
  booktitle={Cancer science},
Cancer is a polygenic disease characterized by uncontrolled growth of normal body cells, deregulation of the cell cycle as well as resistance to apoptosis. The spectraplakin protein microtubule actin cross-linking factor 1 (MACF1) plays an essential function in various cellular processes, including cell proliferation, migration, signaling transduction and embryo development. MACF1 is also involved in processes such as metastatic invasion in which cytoskeleton organization is a critical element… CONTINUE READING
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Knockdown of microtubule actin crosslinking factor 1 inhibits cell proliferation in MC 3 T 3E 1 osteoblastic cells

  • AR Qian, LF Hu, X Gao
  • BMB Rep
  • 2015

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