Microtubule Nucleation at Non-Spindle Pole Body Microtubule-Organizing Centers Requires Fission Yeast Centrosomin-Related Protein mod20p

@article{Sawin2004MicrotubuleNA,
  title={Microtubule Nucleation at Non-Spindle Pole Body Microtubule-Organizing Centers Requires Fission Yeast Centrosomin-Related Protein mod20p},
  author={Kenneth E Sawin and Paula C. C. Lourenço and Hilary A. Snaith},
  journal={Current Biology},
  year={2004},
  volume={14},
  pages={763-775}
}
BACKGROUND Many types of differentiated eukaryotic cells display microtubule distributions consistent with nucleation from noncentrosomal intracellular microtubule organizing centers (MTOCs), although such structures remain poorly characterized. In fission yeast, two types of MTOCs exist in addition to the spindle pole body, the yeast centrosome equivalent. These are the equatorial MTOC, which nucleates microtubules from the cell division site at the end of mitosis, and interphase MTOCs, which… CONTINUE READING
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A fourth Independent work from the laboratory of K. Gould has identified a gamma-tubulin complex-associated protein, mbo1p

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