Microstructured Arrays with Pre-synthesized Capture Probes for DNA Detection Based on Metal Nanoparticles and Silver Enhancement


DNA microarrays exhibiting highly defined squared spot geometry and increased homogeneity in capture DNA distribution were prepared by a combination of microfabrication and DNA spotting. The microfabricated substrates were tested using metal nanoparticles as markers. The optical absorption signal is improved by a silver enhancement step. Experiments… (More)
DOI: 10.1023/B:JOFL.0000031818.39925.4c


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