Microstructure of a spatial map in the entorhinal cortex

@article{Hafting2005MicrostructureOA,
  title={Microstructure of a spatial map in the entorhinal cortex},
  author={Torkel Hafting and Marianne Fyhn and Sturla Molden and May-Britt Moser and Edvard I. Moser},
  journal={Nature},
  year={2005},
  volume={436},
  pages={801-806}
}
The ability to find one's way depends on neural algorithms that integrate information about place, distance and direction, but the implementation of these operations in cortical microcircuits is poorly understood. Here we show that the dorsocaudal medial entorhinal cortex (dMEC) contains a directionally oriented, topographically organized neural map of the spatial environment. Its key unit is the ‘grid cell’, which is activated whenever the animal's position coincides with any vertex of a… CONTINUE READING
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