Microstructure and properties of nano-fibrous PCL-b-PLLA scaffolds for cartilage tissue engineering.

  title={Microstructure and properties of nano-fibrous PCL-b-PLLA scaffolds for cartilage tissue engineering.},
  author={Liumin He and Bin Liu and Guan Xipeng and Gaoyi Xie and S. P. Liao and Daping Quan and Daozhang Cai and Jiang Lu and Seeram Ramakrishna},
  journal={European cells & materials},
Nano-fibrous scaffolds which could potentially mimic the architecture of extracellular matrix (ECM) have been considered a good candidate matrix for cell delivery in tissue engineering applications. In the present study, a semicrystalline diblock copolymer, poly(epsilon-caprolactone)-block-poly(L-lactide) (PCL-b-PLLA), was synthesized and utilized to fabricate nano-fibrous scaffolds via a thermally induced phase separation process. Uniform nano-fibrous networks were created by quenching a PCL-b… CONTINUE READING


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