Microstructural alterations of white matter in juvenile myoclonic epilepsy.

  title={Microstructural alterations of white matter in juvenile myoclonic epilepsy.},
  author={Jinnan Gong and Xuebin Chang and Sisi Jiang and Benjamin Klugah-Brown and Song Tan and Dezhong Yao and Cheng Luo},
  journal={Epilepsy research},
Juvenile myoclonic epilepsy (JME) is a common type of idiopathic generalized epilepsy that is characterized by myoclonic jerks of the upper limbs and generalized tonic-clonic seizures. Frontal cognitive dysfunctions and abnormal coupling of the thalamocortical system have been found in neuropsychological and neuroimaging studies. This study intended to explore white matter (WM) measurement changes in JME using MRI. Twenty-six patients with JME and 25 healthy controls (HC) were recruited for the… CONTINUE READING