Microsomal glutathione transferase 1.

  title={Microsomal glutathione transferase 1.},
  author={Ralf Morgenstern},
  journal={Methods in enzymology},
Microsomal glutathione transferase 1 (MGST1) is an abundant membrane-bound glutathione transferase and peroxidase constituting 3% of the endoplasmic reticulum protein in rat liver (and 5% of the outer mitochondrial membrane). The enzyme is most well studied in mammals and belongs to a large and widely distributed superfamily. Cellular and organelle protection versus oxidative stress has been demonstrated. The enzyme displays activity to a multitude of reactive substrates ranging from products… CONTINUE READING

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