Microsomal ethanol-oxidizing system.

  title={Microsomal ethanol-oxidizing system.},
  author={Charles S. Lieber},
  volume={37 1-2},
Advances in our knowledge of the microsomal metabolism of ethanol enable us to understand a number of complications that develop in the alcoholic. After chronic ethanol consumption, microsomal ethanol-oxidizing system (MEOS) activity increases with an associated rise in microsomal cytochrome P-450, including a form different from that induced by phenobarbital and methylcholanthrene and which has a high affinity for ethanol, as shown in reconstituted systems. The role of this MEOS in vivo and… CONTINUE READING


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