Microscopic tissue alterations following cryosurgery of canine skin.

Cryosurgery of cutaneous tissue of 6 dogs was followed by serial biopsies throughout the necrotizing and healing periods. The duration of cold application was controlled by thermocouple monitoring in 3 dogs and by a standard time in 3 dogs. Tissue changes following cryosurgery were consistent in all 6 dogs and were composed of edema, erythema, necrosis… (More)