Microscopic polyangiitis: clinical aspects and treatment.

  title={Microscopic polyangiitis: clinical aspects and treatment.},
  author={François Lhote and Pascal Cohen and Thierry G{\'e}n{\'e}reau and Martine Gayraud and L{\"o}ic Guillevin},
  journal={Annales de medecine interne},
  volume={147 3},
Recently individualized from polyarteritis nodosa (PAN), microscopic polyangiitis (MPA) is defined as a systemic necrotizing vasculitis that clinically and histologically affects small-sized vessels (ie, capillaries, venules or arterioles) without granulomata and is associated with focal segmental necrotizing glomerulonephritis. Males are more frequently affected than females and the average age of onset is about 50 years old. Most patients experience some systemic symptoms before diagnosis of… CONTINUE READING
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