Microscopic imaging of DNA repair foci in irradiated normal tissues.

Abstract

PURPOSE It is now feasible to detect DNA double strand breaks (DSB) in tissues by measuring the induction and resolution of DNA repair foci, such as gamma-H2AX, using immunofluorescent microscopy and digital image analysis. This review will highlight principal tools and approaches to tissue microscopy and analysis. It will also discuss the practical… (More)
DOI: 10.1080/09553000902785791

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