Corpus ID: 87105315

Microscopic and molecular assessment of chlorhexidine tolerance mechanisms in Delftia acidovorans biofilms

  title={Microscopic and molecular assessment of chlorhexidine tolerance mechanisms in Delftia acidovorans biofilms},
  author={T. Rema},
1 Citations
Antibacterial and Antifungal Activity of Ceragenins, Mimics of Endogenous Antimicrobial Peptides
Antibacterial and Antifungal Activity of Ceragenins, Mimics of Endogenous Antimicrobial Peptides Marjan Mohammadihashemi Department of Chemistry and Biochemistry, BYU Doctor of Philosophy TheExpand


Biofilm formation by coagulase-negative staphylococci: impact on the efficacy of antimicrobials and disinfectants commonly used on dairy farms.
Investigation of the effect of biofilm formation on efficacy of commonly used antibiotics and disinfectants against coagulase-negative staphylococci found CNS biofilms were less susceptible to antibiotics; however, chlorhexidine-based teat disinfectants were still effective against CNS biofilmms, reinforcing the use of post-milking teat chlorine disinfectants as a preventive measure of intramammary infections. Expand
Soft X‐Ray Imaging and Spectromicroscopy
Molecular Mechanisms of Chlorhexidine Tolerance in Burkholderia cenocepacia Biofilms
After sessile cell exposure, multiple genes encoding chemotaxis and motility-related proteins were upregulated in concert with the downregulation of an adhesin-encoding gene (BCAM2143), suggesting that sessiles cells tried to escape the biofilm. Expand
Chlorhexidine‐induced ultrastructural alterations in oral biofilm
It is suggested that the insufficient efficiency of chlorhexidine against oral biofilm is suggested, as well as the need for further research on this topic. Expand
Analysis of the Effects of Chlorhexidine on Oral Biofilm Vitality and Structure Based on Viability Profiling and an Indicator of Membrane Integrity
The possibility of using fluorescent indicators of membrane integrity in conjunction with viability profiling to evaluate the penetration of the bactericidal effects of membrane-active antimicrobial compounds into biofilm is suggested. Expand
Biocide use and antibiotic resistance: the relevance of laboratory findings to clinical and environmental situations.
  • A. D. Russell
  • Biology, Medicine
  • The Lancet. Infectious diseases
  • 2003
Assessment of biocidal activity by bactericidal testing is more relevant than by determination of minimum inhibitory concentrations and translation of such findings to the clinical and environmental situations to provide evidence of a possible relation between biocide use and clinical antibiotic resistance is difficult and should be viewed with caution. Expand
Adaptation and growth of Serratia marcescens in contact lens disinfectant solutions containing chlorhexidine gluconate
Serratia marcescens (11 of 12 strains) demonstrated an ability to grow in certain chlor hexidine-based disinfecting solutions recommended for rigid gas-permeable contact lenses, and cells adapted to chlorhexidine persisted or grew in several other contact lens solutions with different antimicrobial agents, including benzalkonium chloride. Expand
Electron-microscope study of the effect of chlorhexidine on Pseudomonas aeruginosa.
Electron micrographs of cytological damage to log phase Pseudomonas aeruginosa caused by low consentrations of chlorhexidine indicate an action primarily on the cytoplasmic membrane at concentration of 2.0--3.0 micrograms/ml, while evidence of two types of resistance to chlor hexidine is presented. Expand
Biocide tolerance in bacteria.
This review summarizes the main advances reached in understanding the mechanism of action of biocides, the mechanisms of bacterial resistance to both biocide and antibiotics, and the incidence of biocide tolerance in bacteria of concern to human health and the food industry. Expand
Evaluation of the level of microbial contamination and prevalence of gram-negative non-fermentative rods in dental unit waterlines
The cross infection control in dental office has received great attention from professionals and one of the critical points is the bacteriologiography, which identifies the bacteria responsible for cross infection in patients. Expand