Microscale Surgery on Single Axons

  title={Microscale Surgery on Single Axons},
  author={D. Sretavan and W. Chang and Elizabeth A Hawkes and Christopher B. Keller and M. Kliot},
  • D. Sretavan, W. Chang, +2 authors M. Kliot
  • Published 2005
  • Medicine
  • Neurosurgery
  • OBJECTIVE:The lack of meaningful axon regeneration after central nervous system damage and poor functional recovery after serious peripheral nervous system nerve injuries have been long-standing problems of substantial interest to both neurosurgeons and neurobiologists. As an alternative to strategies that seek to promote the regeneration of adult axons, our research group has taken advantage of advances in microtechnology to develop a paradigm of direct axon repair involving the substitution… CONTINUE READING
    30 Citations

    Figures and Topics from this paper.

    Axon repair: surgical application at a subcellular scale.
    • 22
    Development and Application of In Vitro Compartmentalized Devices to Study Axonal Injury
    Investigation of nerve injury through microfluidic devices
    • 34
    • PDF
    An overture to basic science aspects of nerve injuries
    • T. Carlstedt
    • Medicine
    • The Journal of hand surgery, European volume
    • 2011
    • 12
    Controlling Tiny Multi-Scale Robots for Nerve Repair
    • 16
    • PDF
    Nanotechnology in ophthalmology.
    • 61
    The legacy of nanotechnology: revolution and prospects in neurosurgery.
    • 22
    Organ repair and regeneration: an overview.
    • 83


    Neural tissue engineering: strategies for repair and regeneration.
    • 1,019
    • PDF
    Degenerative and regenerative responses of injured neurons in the central nervous system of adult mammals.
    • A. Aguayo, M. Rasminsky, +5 authors D. Carter
    • Biology, Medicine
    • Philosophical transactions of the Royal Society of London. Series B, Biological sciences
    • 1991
    • 165
    Chondroitinase ABC promotes functional recovery after spinal cord injury
    • 1,400
    • PDF
    Transplantation Options for Therapeutic Central Nervous System Remyelination
    • 62
    Remyelination by transplanted olfactory ensheathing cells.
    • R. Franklin
    • Medicine, Biology
    • Anatomical record. Part B, New anatomist
    • 2003
    • 70