Microsatellites, from molecules to populations and back.
- BiologyTrends in ecology & evolution
Microsatellites: evolution and contribution.
- BiologyMethods in molecular biology
This chapter considers genomic distribution, evolution, and practical applications of microsatellites, with special emphasis on plant breeding and agriculture, and novel advances in microsatellite technologies are discussed.
Microsatellite DNA markers , a fi sheries perspective Part 1 : The nature of microsatellites
Microsatellites are abundantly distributed across the genome, demonstrate high levels of allele polymorphism and can easily be amplifi ed with PCR, which provide the underlying basis for their successful application in a wide range of fundamental and applied biology and medicine.
Microsatellites—A New Approach of Marker- Assisted Selection
The ability to detect a much higher level of polymorphism with microsatellites in eukaryotes than with RFLP markers are demonstrated in the work.
Microsatellite markers for the study of cetacean populations
- Biology, Environmental ScienceMolecular ecology
The isolation and characterization of 12 cetacean microsatellites are described and no relationship was found between microsatellite repeat length and proportion of species which gave polymorphic products.
Nonamplifying alleles at microsatellite loci: a caution for parentage and population studies
- BiologyMolecular ecology
While genotyping wild red deer at microsatellite loci for paternity assignment, three loci with segregating nonamplifying alleles were found, and the possible existence of undetectable alleles must be taken into account.
Human microsatellites applicable for analysis of genetic variation in apes and Old World monkeys.
- BiologyThe Journal of heredity
It is confirmed that with the use of appropriate universally applicable PCR conditions, a subset of human microsatellites are informative genetic markers in a wide range of divergent primate taxa.
Evidence for complex mutations at microsatellite loci in Drosophila.
The data indicate that many microsatellite mutation events are more complex than represented even by generalized stepwise mutation models, and care should be taken in inferring population or phylogenetic relationships from micros satellite size data alone.
Evolution and applications of pine microsatellites
- Biology, Environmental Science
Comparison of observed genetic diversities and expected diversities suggested post-bottleneck expansion of populations, suggesting recessive deleterious alleles have been eliminated after bottlenecks and the mating system has changed as a consequence.
SHOWING 1-10 OF 45 REFERENCES
Microsatellites for linkage analysis of genetic traits.
- BiologyTrends in genetics : TIG
Isolation and chromosomal assignment of 100 highly informative human simple sequence repeat polymorphisms.
Hypervariability of simple sequences as a general source for polymorphic DNA markers.
- BiologyNucleic acids research
The polymerase chain reaction (PCR) process is used to show that several randomly chosen simple sequence loci with different nucleotide composition and from different species show extensive length polymorphisms.
DNA polymorphisms amplified by arbitrary primers are useful as genetic markers.
- BiologyNucleic acids research
A new DNA polymorphism assay based on the amplification of random DNA segments with single primers of arbitrary nucleotide sequence is described, suggesting that these polymorphisms be called RAPD markers, after Random Amplified Polymorphic DNA.
Spontaneous mutation rates to new length alleles at tandem-repetitive hypervariable loci in human DNA
The spontaneous mutation rate to new length alleles at extremely variable human minisatellites is sufficiently high to be directly measurable in human pedigrees and Germline instability must therefore be taken into account when using hypervariable loci as genetic markers, particularly in pedigree analysis and parenthood testing.
Variable number of tandem repeat (VNTR) markers for human gene mapping.
Ten oligomeric sequences derived from the tandem repeat regions of the myoglobin gene, the zeta-globin pseudogene, the insulin gene, and the X-gene region of hepatitis B virus were used to develop a series of single-copy probes that revealed new, highly polymorphic genetic loci whose allele sizes reflected variation in the number of tandem repeats.
Genetic variation at five trimeric and tetrameric tandem repeat loci in four human population groups.
The conservation of dinucleotide microsatellites among mammalian genomes allows the use of heterologous PCR primer pairs in closely related species.
A hypervariable microsatellite revealed by in vitro amplification of a dinucleotide repeat within the cardiac muscle actin gene.
- BiologyAmerican journal of human genetics
Using the polymerase chain reaction to amplify a (TG)n microsatellite in the human cardiac actin gene, 12 different allelic fragments in 37 unrelated individuals were detected, 32 of whom were heterozygous and Codominant Mendelian inheritance of fragments was observed in three families with a total of 24 children.
Conservation of polymorphic simple sequence loci in cetacean species
The high conservation of non-coding sequences in whales simplifies the application of SSLP DNA fingerprinting in cetacean species, as primers designed for one species will often uncover variability in other species.