Microsatellite instability detected in tumor-related genes in C57BL/6J mice with thymic lymphoma induced by N-methyl-N-nitrosourea.

@article{Zhang2015MicrosatelliteID,
  title={Microsatellite instability detected in tumor-related genes in C57BL/6J mice with thymic lymphoma induced by N-methyl-N-nitrosourea.},
  author={Shuangyue Zhang and X. Y. Huo and Zhenkun Li and Xiaohong Li and Wang Tang and Changlong Li and Meng Guo and Xiaoyan Du and Zhenwen Chen},
  journal={Mutation research},
  year={2015},
  volume={782},
  pages={7-16}
}
Microsatellite instability (MSI) has been observed within tumors and found to be closely associated with the degree of malignancy and prognosis in tumors. However, whether MSI in tumor-related genes can be induced by a chemical and whether a connection exists between MSI and tumors remain unclear. In the present study, we detected MSI in the tissues of N… CONTINUE READING