Microsatellite analysis of endometriosis reveals loss of heterozygosity at candidate ovarian tumor suppressor gene loci.

@article{Jiang1996MicrosatelliteAO,
  title={Microsatellite analysis of endometriosis reveals loss of heterozygosity at candidate ovarian tumor suppressor gene loci.},
  author={Xiuxian Jiang and Andrew Hitchcock and Emma J. Bryan and Richard H Watson and P. Englefield and Eric J. Thomas and Ian G. Campbell},
  journal={Cancer research},
  year={1996},
  volume={56 15},
  pages={3534-9}
}
Endometriosis is a very common gynecological condition in which tissue similar to endometrium proliferates at sites outside the uterine cavity, most commonly the ovary. Although it generally remains a benign condition, malignant transformation has been documented. and it is commonly found in association with endometrioid subtype ovarian cancer. Tumor suppressor genes are commonly altered in ovarian cancers, and the development of endometriosis may involve mutations in the same class of genes… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 35 references

Allelic imbalance of chromo some 6 q in ovarian tumors

V. Orphanos, Y. Hey, +5 authors J. M. Boyle
Br . J . Cancer • 1995

Familial endometriosis

Journal of Assisted Reproduction and Genetics • 1995

MDM 2 overexpression is rare in ovarian carcinoma irrespec tive of TP 53 mutation status

W. D. Foulkes, 0. W. H. Stamp, +3 authors J. Trowsdale
Br . J . Cancer • 1995

Monoclonal origin of endometriotic cysts.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society • 1995

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