Microsatellite Instability, KRAS Mutations and Cellular Distribution of TRAIL-Receptors in Early Stage Colorectal Cancer

@inproceedings{Kriegl2012MicrosatelliteIK,
  title={Microsatellite Instability, KRAS Mutations and Cellular Distribution of TRAIL-Receptors in Early Stage Colorectal Cancer},
  author={Lydia Kriegl and Andreas Jung and David Horst and Antonia Rizzani and Rene Jackstadt and Heiko Hermeking and Eike Gallmeier and Alexander L Gerbes and Thomas W. Kirchner and Burkhard J. G{\"o}ke and Enrico Narciso De Toni},
  booktitle={PloS one},
  year={2012}
}
BACKGROUND The fact that the receptors for the TNF-related apoptosis inducing ligand (TRAIL) are almost invariably expressed in colorectal cancer (CRC) represents the rationale for the employment of TRAIL-receptors targeting compounds for the therapy of patients affected by this tumor. Yet, first reports on the use of these bioactive agents provided… CONTINUE READING