Microsatellite (GT)(n) repeats and SNPs in the von Willebrand factor gene promoter do not influence circulating von Willebrand factor levels under normal conditions.

@article{Daidone2009MicrosatelliteR,
  title={Microsatellite (GT)(n) repeats and SNPs in the von Willebrand factor gene promoter do not influence circulating von Willebrand factor levels under normal conditions.},
  author={Viviana Daidone and Maria Grazia Cattini and Elena Pontara and Francesca Sartorello and Lisa Gallinaro and Alberto Marotti and C Scaroni and Antonio Pagnan and Alessandra Casonato},
  journal={Thrombosis and haemostasis},
  year={2009},
  volume={101 2},
  pages={298-304}
}
Von Willebrand factor (VWF) levels vary considerably in normal individuals, influenced by inherited and acquired modulators. ABO blood group is the major inherited determinant of VWF levels, but a role has also been attributed to the VWF gene promoter, haplotype 1 (-3268G/-2709C/-2661A/-2527G) being associated with higher VWF levels than haplotype 2 (-3268C… CONTINUE READING