Micropthalmia transcription factor: a new prognostic marker in intermediate-thickness cutaneous malignant melanoma.

@article{Salti2000MicropthalmiaTF,
  title={Micropthalmia transcription factor: a new prognostic marker in intermediate-thickness cutaneous malignant melanoma.},
  author={George I. Salti and Taline Manougian and Miguel Farolan and Anne Shilkaitis and Dibyen Majumdar and Tapas K. Das Gupta},
  journal={Cancer research},
  year={2000},
  volume={60 18},
  pages={5012-6}
}
Micropthalmia transcription factor (Mitf) is involved in melanocyte development and differentiation. The current study was undertaken to determine whether there is a relationship between Mitf expression and survival in patients with intermediate-thickness (1.0-4.0 mm) melanoma. Original paraffin blocks or slides of the primary tumor were accessible in 63 such patients. Mitf expression was evaluated by immunocytochemistry and analyzed visually. Slides were graded as follows according to the… CONTINUE READING
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