Microphase Behavior and Enhanced Wet-Cohesion of Synthetic Copolyampholytes Inspired by a Mussel Foot Protein.

@article{Seo2015MicrophaseBA,
  title={Microphase Behavior and Enhanced Wet-Cohesion of Synthetic Copolyampholytes Inspired by a Mussel Foot Protein.},
  author={Sungbaek Seo and Saurabh Das and Piotr Zalicki and Razieh Mirshafian and Claus D Eisenbach and Jacob N. Israelachvili and J. Herbert Waite and B. Kollbe Ahn},
  journal={Journal of the American Chemical Society},
  year={2015},
  volume={137 29},
  pages={
          9214-7
        }
}
Numerous attempts have been made to translate mussel adhesion to diverse synthetic platforms. However, the translation remains largely limited to the Dopa (3,4-dihydroxyphenylalanine) or catechol functionality, which continues to raise concerns about Dopa's inherent susceptibility to oxidation. Mussels have evolved adaptations to stabilize Dopa against oxidation. For example, in mussel foot protein 3 slow (mfp-3s, one of two electrophoretically distinct interfacial adhesive proteins in mussel… 

Recent progress in synthesis and application of mussel-inspired adhesives.

An overview of the unique features of various mussel foot proteins is provided in combination with an up-to-date understanding of catechol chemistry, which contributes to the strong interfacial binding via balancing a variety of covalent and noncovalent interactions.

Inter- and intramolecular adhesion mechanisms of mussel foot proteins

A brief review of the research progress on the adhesion mechanisms of Mfps is presented, which further emphasizes the contributions of Dopa-mediated interactions and considers other amino acids and factors.

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The initial contact adhesion properties of copolymerized acrylate films containing the key functionalities of barnacle cement proteins and interfacial mfps, for example, aromatic, cationic, anionic, and nonpolar residues, were studied, suggesting viability for biomedical applications.

Recent approaches in designing bioadhesive materials inspired by mussel adhesive protein

Recent findings on the contributions of various features of Mfps on interfacial binding, which include coacervate formation, surface drying properties, control of the oxidation state of catechol, among other features are reviewed.

High-performance mussel-inspired adhesives of reduced complexity

This study significantly simplifies bio-inspired themes for wet adhesion by combining catechol with hydrophobic and electrostatic functional groups in a small molecule.

Coacervation of Interfacial Adhesive Proteins for Initial Mussel Adhesion to a Wet Surface.

This study shows enthalpy driven upper critical solution temperature behavior, possibly relying on bridging interactions between like-charged cationic fp-3Fs including salt-bridge and cation-π/π-π interactions in the presence of specific counterions, supported by Raman spectroscopy.

Direct Observation of the Interplay of Catechol Binding and Polymer Hydrophobicity in a Mussel-Inspired Elastomeric Adhesive

The observation of the synergy between catechol binding and hydrophobicity in enabling the mussel-inspired soft adhesive elastomer to stick underwater provides a framework for designing materials for applications in tissue adhesion and moist-skin wearable electronics.

Biomimetic Adhesives and Coatings Based on Mussel Adhesive Proteins

Modification of inert polymer systems with DOPA and other catechol derivatives have imparted materials with water-resistant adhesive properties and the ability to cure rapidly, as well as recent developments of self-healing and smart materials that employ MAP chemistry.

Peptide Length and Dopa Determine Iron‐Mediated Cohesion of Mussel Foot Proteins

It is shown that Dopa in a peptide sequence does not by itself mediate Fe3+ bridging interactions between peptide films: peptide length is a crucial enabling factor.
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References

SHOWING 1-10 OF 22 REFERENCES

Hydrophobic enhancement of Dopa-mediated adhesion in a mussel foot protein.

Using a surface forces apparatus to investigate the adhesion of mussel foot protein 3 (Mfp3) "slow", a hydrophobic protein variant of the Mfp3 family in the plaque, a subtle molecular strategy correlated with hydrophobicity that appears to compensate for Dopa instability is discovered.

Polymer composition and substrate influences on the adhesive bonding of a biomimetic, cross-linking polymer.

The adhesive bonding of poly[(3,4-dihydroxystyrene)-co-styrene] may be the strongest of reported mussel protein mimics, bringing us closer to development of bone cements, dental composites, and surgical glues.

Interfacial pH during mussel adhesive plaque formation

To probe the interfacial pH at which mussels buffer the local environment during mfp deposition, a lipid bilayer with tethered pH-sensitive fluorochromes was assembled on mica and served multiple functions: it limits mfp-Dopa oxidation, thereby enabling the catecholic functionalities to adsorb to surface oxides by H-bonding and metal ion coordination, and provides a solubility switch for mfps.

Tough coating proteins: subtle sequence variation modulates cohesion.

Mussel foot protein-1 (mfp-1) is an essential constituent of the protective cuticle covering all exposed portions of the byssus (plaque and the thread) that marine mussels use to attach to intertidal

Adhesion of mussel foot protein Mefp-5 to mica: an underwater superglue.

Using the surface forces apparatus, it is shown that on mica surfaces Mefp-5 achieves an adhesion energy approaching E(ad) = ~-14 mJ/m(2) and is greater than the adhesion between highly oriented monolayers of biotin and streptavidin.

Asymmetric collapse in biomimetic complex coacervates revealed by local polymer and water dynamics.

This study employs the novel magnetic resonance technique Overhauser dynamic nuclear polarization enhanced nuclear magnetic resonance (DNP), together with electron paramagnetic resonance (EPR) line shape analysis, to concurrently quantify local molecular and hydration dynamics, with species- and site-specificity.

Natural Underwater Adhesives.

Empirical evidence suggests environment triggers could provide minimalistic, fail-safe timing mechanisms to prevent premature solidification (insolubilization) of the glue within the secretory system, yet allow rapid solidification after secretion.

Synthesis and gelation of DOPA-modified poly(ethylene glycol) hydrogels.

3,4-Dihydroxyphenylalanine (DOPA) residues are known for their ability to impart adhesive and curing properties to mussel adhesive proteins. In this paper, we report the preparation of linear and

Strong underwater adhesives made by self-assembling multi-protein nanofibres.

Strong and multi-functional underwater adhesives obtained from fusing mussel foot proteins of Mytilus galloprovincialis with CsgA proteins, the major subunit of Escherichia coli amyloid curli fibres are reported.